NTN3

Across TCGA patient cohorts, NTN3 mutation is significantly associated with the total protein of many other genes, with 4 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NTN3-associated genes across cancer lineages are Ku80, TIGAR, and Tuberin. Each is linked with NTN3 in more than 1 cancer types. Because this analysis shows association rather than direction, both NTN3-to-partner and partner-to-NTN3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Ku80 grouped by NTN3-low versus NTN3-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NTN3→partner) and Y-score (partner→NTN3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Ku80 →	+0.336	+2.820	.020	.036	2	1
UCEC	TIGAR →	+0.191	+2.833	.041	.035	2	1
UCEC	Tuberin →	+0.489	+2.817	.003	.036	2	1
UCEC	Myosin-IIa_pS1943 →	+0.258	+2.820	.041	.036	1	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

Ku80 by NTN3 expression — UCEC

Explore this box plot interactively →