NTN3

Across TCGA pan-cancer cohorts, NTN3 RNA is linked to patient survival in 26 of 34 cancer types, making it the most broadly survival-associated NTN3 data layer compared with 4 for mutation status.

The strongest signal is observed in uterine carcinosarcoma (UCS), where higher NTN3 RNA is associated with better overall survival. In most high-consensus cancer types, elevated NTN3 expression acts as an unfavorable survival marker, although some lineages such as UCS and SCLC show a favorable association.

UCS, KIRP, and ACC are the cancer types where NTN3 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCS	OS	Median	II,III,IV	0.658	0.200	<.001	108	view →
KIRP	OS	Median	II,III,IV	0.354	0.759	<.001	74	view →
ACC	OS	Median	All	0.767	0.968	<.001	50	view →
SCLC	OS	Quartile	All	0.806	0.441	.001	47	view →
KIRC	DFS	Quartile	II,III,IV	0.666	0.848	.004	35	view →
BLCA	DFS	Tertile	All	0.261	0.428	.008	30	view →
UVM	DFS	Tertile	All	0.459	0.929	.004	26	view →
BRCA	DFS	Quartile	All	0.484	0.642	.008	24	view →
ESCA	OS	Tertile	All	1.000	0.456	.014	24	view →
LUSC	DFS	Quartile	III,IV	0.296	0.951	.003	23	view →
SKCM	DFS	Tertile	III,IV	0.689	0.534	.011	22	view →
CHOL	DFS	Tertile	II,III,IV	0.140	0.607	.006	17	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 26 lineages.

NTN3–UCS (OS)

Open the UCS breakdown →