NTN3

Across TCGA cell cohorts, NTN3 mutation is significantly associated with the RNA expression of many other genes, with 17 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible NTN3-associated genes across cancer lineages are PRAMEF10, KRTAP10-4, and PRAMEF18. Each is linked with NTN3 in more than 1 cancer types. Because this analysis shows association rather than direction, both NTN3-to-partner and partner-to-NTN3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PRAMEF10 grouped by NTN3-low versus NTN3-high in SOFT_TISSUE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NTN3→partner) and Y-score (partner→NTN3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	PRAMEF10 →	+0.022	+4.930	<.001	.008	3	1
SOFT_TISSUE	KRTAP10-4 →	+0.018	+4.930	.004	.008	3	1
SOFT_TISSUE	PRAMEF18 →	+0.026	+4.930	<.001	.008	3	1
LARGE_INTESTINE	MAGEB4 →	+0.024	+6.000	<.001	<.001	3	1
LARGE_INTESTINE	STRA8 →	+0.161	+4.415	<.001	.007	3	1
LARGE_INTESTINE	ZNF804B →	+0.016	+4.415	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 17 associations by consensus.

PRAMEF10 by NTN3 expression — SOFT_TISSUE

Explore this box plot interactively →