NTN1

Across TCGA pan-cancer cohorts, NTN1 mass-spec protein is linked to patient survival in 6 of 34 cancer types, making it a survival-associated NTN1 data layer compared with 26 for mass-spec protein and 3 for mutation status.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher NTN1 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated NTN1 expression acts as an unfavorable survival marker, although some lineages such as LSCC and PDAC show a favorable association.

LUAD, LSCC, and CCRCC are the cancer types where NTN1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	DFS	Quartile	II,III,IV	0.680	0.923	.010	26	view →
LSCC	DFS	Tertile	III,IV	1.000	0.503	.002	16	view →
CCRCC	DFS	Median	All	0.664	1.000	.028	7	view →
HNSC	OS	Median	All	0.957	1.000	.017	7	view →
PDAC	OS	Median	All	0.701	0.428	.016	6	view →
UCEC	DFS	Median	III,IV	0.494	0.905	.044	4	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

NTN1–LUAD (DFS)

Open the LUAD breakdown →