NTN1

Across TCGA pan-cancer cohorts, NTN1 RNA differs between tumor and matched normal tissue in 13 of 18 cancer types tested, making tumor–normal expression one of NTN1’s most consistent transcriptional readouts.

The strongest signal is observed in colon adenocarcinoma (COAD), where NTN1 RNA is repressed in tumor relative to normal tissue. In most cancer types NTN1 is over-expressed in tumor, although a few such as COAD and KIRC show the opposite, repressed pattern.

COAD, KIRC, and THCA are the cancer types where NTN1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in NTN1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
COAD	Female	III,IV	−2.394	<.001	12	view →
KIRC	Male	III,IV	−1.307	<.001	12	view →
THCA	Female	II,III,IV	−1.352	<.001	10	view →
KICH	Male	All	+2.970	<.001	9	view →
BLCA	Male	All	−1.781	<.001	9	view →
KIRP	Male	All	−1.369	<.001	7	view →
BRCA	All	II,III,IV	−0.460	.002	6	view →
STAD	All	All	−1.536	<.001	5	view →
LIHC	All	All	+0.588	<.001	5	view →
LUSC	All	All	+0.924	<.001	4	view →
READ	All	All	−2.355	<.001	3	view →
PRAD	All	All	−0.659	.001	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 13 lineages.

NTN1–COAD

Open the COAD breakdown →