NTN1

Across TCGA patient cohorts, NTN1 RNA expression is significantly associated with the go_rna of many other GO terms, with 7,167 significant associations in total. PRAD shows the largest number of these associations.

The most reproducible NTN1-associated GO terms across cancer lineages are Insulin receptor signaling pathway, Hippo signaling, and Regulation of cell-substrate junction organization. Each is linked with NTN1 in more than 24 cancer types. Because this analysis shows association rather than direction, both NTN1-to-partner and partner-to-NTN1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Insulin receptor signaling pathway grouped by NTN1-low versus NTN1-high in SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NTN1→partner) and Y-score (partner→NTN1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SCLC	Insulin receptor signaling pathway →	+0.089	+1.596	<.001	<.001	3	25
SCLC	Hippo signaling →	+0.087	+1.301	.001	<.001	3	24
TGCT	Regulation of cell-substrate junction organization →	+0.077	+2.273	<.001	<.001	3	24
THYM	Regulation of cell-substrate adhesion →	+0.052	+2.404	<.001	<.001	3	23
THYM	Epithelial cell development →	+0.059	+2.519	<.001	<.001	3	23
TGCT	Heart morphogenesis →	+0.072	+2.199	<.001	<.001	3	23

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,167 associations by consensus.

Insulin receptor signaling pathway by NTN1 expression — SCLC

Explore this box plot interactively →