NTN1

Across TCGA cell cohorts, NTN1 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,915 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible NTN1-associated GO terms across cancer lineages are Regulation of lysosomal membrane permeability, Heterochromatin organization, and Epigenetic regulation of gene expression. Each is linked with NTN1 in more than 7 cancer types. Because this analysis shows association rather than direction, both NTN1-to-partner and partner-to-NTN1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of lysosomal membrane permeability grouped by NTN1-low versus NTN1-high in LIVER.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NTN1→partner) and Y-score (partner→NTN1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIVER	Regulation of lysosomal membrane permeability →	+0.156	+1.161	.002	.004	3	8
UPPER_AERODIGESTIVE_TRACT	Heterochromatin organization →	+0.044	+1.902	.005	<.001	3	8
UPPER_AERODIGESTIVE_TRACT	Epigenetic regulation of gene expression →	+0.044	+1.877	.001	<.001	3	8
LUNG_NSCLC_LUSC	Regulation of RNA export from nucleus →	+0.100	+1.711	.002	.009	2	8
STOMACH	Chemorepulsion of axon →	-0.243	-1.098	<.001	<.001	3	7
KIDNEY	Substrate-dependent cell migration, cell extension →	-0.236	-1.414	.001	.004	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,915 associations by consensus.

Regulation of lysosomal membrane permeability by NTN1 expression — LIVER

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