NTMT1

Across TCGA pan-cancer cohorts, NTMT1 mass-spec protein is linked to patient survival in 7 of 34 cancer types, making it a survival-associated NTMT1 data layer compared with 25 for mass-spec protein and 1 for mutation status.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where higher NTMT1 mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated NTMT1 expression acts as an unfavorable survival marker, although some lineages such as HNSC and LSCC show a favorable association.

CCRCC, COAD, and LUAD are the cancer types where NTMT1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CCRCC	OS	Tertile	II,III,IV	0.527	0.913	.002	43	view →
COAD	DFS	Median	II,III,IV	0.907	1.000	.008	42	view →
LUAD	OS	Quartile	All	0.604	0.967	.005	14	view →
PDAC	DFS	Quartile	II,III,IV	0.238	0.510	.012	7	view →
GBM	DFS	Tertile	All	0.668	0.797	.039	1	view →
HNSC	OS	Median	IV	0.926	0.754	.045	1	view →
LSCC	OS	Quartile	II,III,IV	0.929	0.614	.033	1	view →

Pink = unfavorable, green = favorable. Showing the 7 strongest of 7 lineages.

NTMT1–CCRCC (OS)

Open the CCRCC breakdown →