NTMT1

Across TCGA pan-cancer cohorts, NTMT1 RNA differs between tumor and matched normal tissue in 15 of 18 cancer types tested, making tumor–normal expression one of NTMT1’s most consistent transcriptional readouts.

The strongest signal is observed in colon adenocarcinoma (COAD), where NTMT1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types NTMT1 is over-expressed in tumor, although a few such as KIRC show the opposite, repressed pattern.

COAD, HNSC, and LIHC are the cancer types where NTMT1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in NTMT1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
COAD	Female	II,III,IV	+1.618	<.001	12	view →
HNSC	Male	IV	+1.143	<.001	11	view →
LIHC	Male	II,III,IV	+0.913	<.001	9	view →
LUAD	Male	II,III,IV	+0.839	<.001	9	view →
LUSC	Male	II,III,IV	+0.873	<.001	8	view →
READ	All	All	+1.152	<.001	7	view →
STAD	Male	II,III,IV	+0.957	<.001	6	view →
BLCA	All	All	+0.505	.005	6	view →
BRCA	All	All	+0.383	<.001	6	view →
ESCA	All	All	+0.958	.001	5	view →
KIRC	All	II,III,IV	−0.292	.002	5	view →
THCA	Male	All	+0.370	<.001	3	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 15 lineages.

NTMT1–COAD

Open the COAD breakdown →