NTMT1

Across TCGA patient cohorts, NTMT1 mutation is significantly associated with the RNA expression of many other genes, with 229 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NTMT1-associated genes across cancer lineages are OR4K1, OR6U2P, and TP53TG3. Each is linked with NTMT1 in more than 1 cancer types. Because this analysis shows association rather than direction, both NTMT1-to-partner and partner-to-NTMT1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR4K1 grouped by NTMT1-low versus NTMT1-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NTMT1→partner) and Y-score (partner→NTMT1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	OR4K1 →	+0.066	+5.721	.001	.001	3	2
COAD	OR6U2P →	+0.126	+6.409	<.001	<.001	3	2
CESC	TP53TG3 →	+0.042	+5.306	<.001	.006	3	1
CESC	RNA5SP321 →	+0.319	+5.539	<.001	.004	3	1
CESC	RNU4-73P →	+0.381	+5.812	<.001	.003	3	1
CESC	TRAJ29 →	+0.509	+5.010	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 229 associations by consensus.

OR4K1 by NTMT1 expression — COAD

Explore this box plot interactively →