NTMT1

Across TCGA patient cohorts, NTMT1 mutation is significantly associated with the immune_cell of many other genes, with 4 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NTMT1-associated genes across cancer lineages are CD8+ Tcm, HSC, and Basophils. Each is linked with NTMT1 in more than 1 cancer types. Because this analysis shows association rather than direction, both NTMT1-to-partner and partner-to-NTMT1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CD8+ Tcm grouped by NTMT1-low versus NTMT1-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NTMT1→partner) and Y-score (partner→NTMT1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	CD8+ Tcm →	+0.201	+3.918	<.001	.036	3	2
UCEC	HSC →	+0.174	+3.330	<.001	.005	3	1
UCEC	Basophils →	+0.207	+2.459	.011	.020	3	1
UCEC	Smooth muscle →	-0.132	-2.983	.029	.036	3	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

CD8+ Tcm by NTMT1 expression — CESC

Explore this box plot interactively →