NTM-IT

Across TCGA pan-cancer cohorts, NTM-IT RNA is linked to patient survival in 14 of 34 cancer types, making it the most broadly survival-associated NTM-IT data layer.

The strongest signal is observed in uterine carcinosarcoma (UCS), where higher NTM-IT RNA is associated with worse overall survival. In most high-consensus cancer types, elevated NTM-IT expression acts as an unfavorable survival marker, although some lineages such as ESCA and SKCM show a favorable association.

UCS, BLCA, and UCEC are the cancer types where NTM-IT RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCS	OS	Tertile	All	0.102	0.688	<.001	108	view →
BLCA	OS	Tertile	All	0.208	0.620	.014	36	view →
UCEC	OS	Tertile	III,IV	0.660	0.848	.003	36	view →
LUSC	OS	Tertile	All	0.322	0.733	.004	27	view →
THCA	OS	Tertile	III,IV	0.805	0.977	.020	18	view →
SARC	DFS	Tertile	All	0.198	0.523	.005	18	view →
LAML	DFS	Tertile	All	0.221	0.587	.049	18	view →
ESCA	OS	Tertile	III,IV	0.661	0.360	.022	15	view →
SKCM	OS	Tertile	II,III,IV	1.000	0.724	.026	12	view →
PRAD	OS	Tertile	All	0.953	0.995	.012	12	view →
GBM	OS	Tertile	All	0.126	0.421	.020	9	view →
STAD	DFS	Tertile	IV	0.083	0.379	.001	9	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 14 lineages.

NTM-IT–UCS (OS)

Open the UCS breakdown →