NTM-IT

Across TCGA pan-cancer cohorts, NTM-IT RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of NTM-IT’s most consistent transcriptional readouts.

The strongest signal is observed in lung squamous cell carcinoma (LUSC), where NTM-IT RNA is repressed in tumor relative to normal tissue. In most cancer types NTM-IT is over-expressed in tumor, although a few such as LUSC show the opposite, repressed pattern.

LUSC and HNSC are the cancer types where NTM-IT tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in NTM-IT RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LUSC	All	All	−0.038	.001	3	view →
HNSC	Male	III,IV	+0.091	.048	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 2 strongest of 2 lineages.

NTM-IT–LUSC

Open the LUSC breakdown →