Across TCGA patient cohorts, NTF4 mutation is significantly associated with the RNA expression of many other genes, with 513 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NTF4-associated genes across cancer lineages are ACSL1, GUF1, and PDK1. Each is linked with NTF4 in more than 1 cancer types. Because this analysis shows association rather than direction, both NTF4-to-partner and partner-to-NTF4 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NTF4→partner) and Y-score (partner→NTF4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ACSL1 →	+1.176	+3.201	<.001	.009	3	1
UCEC	GUF1 →	+0.574	+3.470	.001	.003	3	1
UCEC	PDK1 →	+0.793	+3.338	.001	.005	3	1
UCEC	SAR1B →	+0.649	+3.459	<.001	.005	3	1
UCEC	CD8A →	+1.200	+3.480	.001	.002	3	1
UCEC	GBP5 →	+1.500	+3.470	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 513 associations by consensus.

Exploration

NTF4 survival (RNA) · tumor vs normal (RNA) · all NTF4 data types