Across TCGA pan-cancer cohorts, NTF4 RNA is linked to patient survival in 28 of 34 cancer types, making it the most broadly survival-associated NTF4 data layer compared with 2 for mutation status.
The strongest signal is observed in colon adenocarcinoma (COAD), where higher NTF4 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated NTF4 expression acts as an unfavorable survival marker, although some lineages such as THYM and BLCA show a favorable association.
COAD, KIRC, and PAAD are the cancer types where NTF4 RNA most reproducibly stratifies survival.
RNA survival associations by lineage
Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.