NTAQ1

Across TCGA pan-cancer cohorts, NTAQ1 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated NTAQ1 data layer compared with 24 for mass-spec protein and 4 for mutation status.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher NTAQ1 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated NTAQ1 expression acts as an unfavorable survival marker, although some lineages such as LSCC show a favorable association.

HNSC, LSCC, and LUAD are the cancer types where NTAQ1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	DFS	Median	II,III,IV	0.452	0.847	<.001	31	view →
LSCC	DFS	Tertile	All	0.853	0.494	<.001	28	view →
LUAD	DFS	Quartile	All	0.885	0.981	.002	23	view →
PDAC	OS	Median	II,III,IV	0.455	0.763	.025	8	view →
GBM	DFS	Median	All	0.668	0.844	.026	1	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

NTAQ1–HNSC (DFS)

Open the HNSC breakdown →