NTAQ1

Across TCGA pan-cancer cohorts, NTAQ1 RNA differs between tumor and matched normal tissue in 14 of 18 cancer types tested, making tumor–normal expression one of NTAQ1’s most consistent transcriptional readouts.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where NTAQ1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types NTAQ1 is over-expressed in tumor, although a few such as KICH and KIRC show the opposite, repressed pattern.

HNSC, COAD, and LIHC are the cancer types where NTAQ1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in NTAQ1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
HNSC	Male	IV	+0.956	<.001	12	view →
COAD	Male	IV	+1.176	<.001	11	view →
LIHC	Male	II,III,IV	+1.580	<.001	9	view →
LUAD	Male	II,III,IV	+0.993	<.001	9	view →
LUSC	Female	All	+1.157	<.001	8	view →
BLCA	All	All	+0.631	<.001	8	view →
UCEC	All	IV	+1.375	.005	6	view →
BRCA	All	III,IV	+0.815	<.001	6	view →
CHOL	All	II,III,IV	+2.405	<.001	5	view →
READ	All	II,III,IV	+1.102	<.001	5	view →
STAD	All	II,III,IV	+0.665	<.001	4	view →
KICH	Female	All	−0.859	<.001	3	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 14 lineages.

NTAQ1–HNSC

Open the HNSC breakdown →