NTAQ1

Across TCGA patient cohorts, NTAQ1 mutation is significantly associated with the total protein of many other genes, with 4 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NTAQ1-associated genes across cancer lineages are Notch1, Caspase-8, and MEK1. Each is linked with NTAQ1 in more than 1 cancer types. Because this analysis shows association rather than direction, both NTAQ1-to-partner and partner-to-NTAQ1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Notch1 grouped by NTAQ1-low versus NTAQ1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NTAQ1→partner) and Y-score (partner→NTAQ1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Notch1 →	+0.153	+3.321	.038	.010	3	1
UCEC	Caspase-8 →	-0.268	-2.973	.042	.035	3	1
UCEC	MEK1 →	+0.543	+3.321	.004	.010	2	1
UCEC	p38-MAPK_pT180_Y182 →	-0.528	-3.000	.025	.036	2	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

Notch1 by NTAQ1 expression — UCEC

Explore this box plot interactively →