Across TCGA patient cohorts, NT5M mutation is significantly associated with the RNA expression of many other genes, with 73 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NT5M-associated genes across cancer lineages are RNU6-698P, MIR6766, and RN7SL680P. Each is linked with NT5M in more than 1 cancer types. Because this analysis shows association rather than direction, both NT5M-to-partner and partner-to-NT5M results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NT5M→partner) and Y-score (partner→NT5M) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNU6-698P →	+0.287	+4.660	<.001	.003	3	2
UCEC	MIR6766 →	+0.407	+3.621	<.001	.004	3	1
UCEC	RN7SL680P →	+0.264	+3.396	<.001	.006	3	1
BRCA	OR5M13P →	+0.029	+8.055	.004	.007	3	1
BRCA	TGIF2LY →	+0.044	+7.731	<.001	.009	3	1
BRCA	SNORD115-47 →	+0.282	+7.731	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 73 associations by consensus.

Exploration

NT5M survival (RNA) · tumor vs normal (RNA) · all NT5M data types