Across TCGA pan-cancer cohorts, NT5M RNA is linked to patient survival in 24 of 34 cancer types, making it the most broadly survival-associated NT5M data layer compared with 3 for mutation status and 1 for mass-spec protein.
The strongest signal is observed in adrenocortical carcinoma (ACC), where higher NT5M RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated NT5M expression acts as an unfavorable survival marker, although some lineages such as OV and PAAD show a favorable association.
ACC, UVM, and BLCA are the cancer types where NT5M RNA most reproducibly stratifies survival.
RNA survival associations by lineage
Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.