Across TCGA cell cohorts, NT5M mutation is significantly associated with the mutation status of many other genes, with 1,031 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible NT5M-associated genes across cancer lineages are TOP1MT, RNF208, and IFRD2. Each is linked with NT5M in more than 2 cancer types. Because this analysis shows association rather than direction, both NT5M-to-partner and partner-to-NT5M results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NT5M→partner) and Y-score (partner→NT5M) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	TOP1MT →	+4.000	+5.050	.008	.008	1	3
BLOOD_Leukemia	RNF208 →	+5.321	+5.894	.002	.002	1	2
BLOOD_Leukemia	IFRD2 →	+4.000	+5.050	.008	.008	1	2
BLOOD_Leukemia	HAUS5 →	+4.321	+5.285	.005	.005	1	2
BLOOD_Leukemia	P2RX5-TAX1BP3 →	+4.000	+5.050	.008	.008	1	2
BLOOD_Leukemia	SCO2 →	+4.736	+5.560	.003	.003	1	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,031 associations by consensus.

Exploration

NT5M survival (RNA) · tumor vs normal (RNA) · all NT5M data types