NT5E

Across TCGA patient cohorts, NT5E mutation is significantly associated with the RNA expression of many other genes, with 2,345 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NT5E-associated genes across cancer lineages are LINC02663, MIR549A, and TEX36-AS1. Each is linked with NT5E in more than 2 cancer types. Because this analysis shows association rather than direction, both NT5E-to-partner and partner-to-NT5E results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LINC02663 grouped by NT5E-low versus NT5E-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NT5E→partner) and Y-score (partner→NT5E) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	LINC02663 →	+0.274	+5.221	.003	.001	3	3
CESC	MIR549A →	+0.299	+4.757	<.001	.004	3	3
LUAD	TEX36-AS1 →	+0.053	+4.730	<.001	.005	3	3
LUSC	MTND6P9 →	+0.105	+4.150	.006	.003	3	3
COAD	GM2AP2 →	+0.112	+5.122	<.001	.004	3	2
COAD	SYPL1P1 →	+0.111	+4.693	<.001	.007	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,345 associations by consensus.

LINC02663 by NT5E expression — COAD

Explore this box plot interactively →