NT5E

Across TCGA cell cohorts, NT5E RNA expression is significantly associated with the go_rna of many other GO terms, with 5,974 significant associations in total. BONE shows the largest number of these associations.

The most reproducible NT5E-associated GO terms across cancer lineages are Regulation of hemostasis, Regulation of blood coagulation, and Urokinase plasminogen activator signaling pathway. Each is linked with NT5E in more than 15 cancer types. Because this analysis shows association rather than direction, both NT5E-to-partner and partner-to-NT5E results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of hemostasis grouped by NT5E-low versus NT5E-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NT5E→partner) and Y-score (partner→NT5E) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Regulation of hemostasis →	+0.216	+4.234	<.001	<.001	3	16
BONE	Regulation of blood coagulation →	+0.212	+4.234	<.001	<.001	3	16
LUNG_NSCLC_LUSC	Urokinase plasminogen activator signaling pathway →	+1.515	+4.594	.001	<.001	3	15
OESOPHAGUS	Positive regulation of chemotaxis →	+0.136	+2.552	<.001	.007	3	15
BONE	Regulation of plasminogen activation →	+0.316	+4.740	<.001	<.001	3	14
BONE	Negative regulation of actin filament depolymerization →	+0.169	+3.423	<.001	<.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,974 associations by consensus.

Regulation of hemostasis by NT5E expression — BONE

Explore this box plot interactively →