NT5DC4

Across TCGA patient cohorts, NT5DC4 mutation is significantly associated with the total protein of many other genes, with 3 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NT5DC4-associated genes across cancer lineages are Ku80, beta-Catenin, and Chk2_pT68. Each is linked with NT5DC4 in more than 1 cancer types. Because this analysis shows association rather than direction, both NT5DC4-to-partner and partner-to-NT5DC4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Ku80 grouped by NT5DC4-low versus NT5DC4-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NT5DC4→partner) and Y-score (partner→NT5DC4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Ku80 →	+0.329	+3.013	.015	.019	2	1
UCEC	beta-Catenin →	+0.636	+3.000	.029	.037	1	1
UCEC	Chk2_pT68 →	-0.221	-3.000	.040	.037	1	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

Ku80 by NT5DC4 expression — UCEC

Explore this box plot interactively →