NT5DC4

Across TCGA cell cohorts, NT5DC4 mutation is significantly associated with the RNA expression of many other genes, with 6 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible NT5DC4-associated genes across cancer lineages are OR1L1, PRAMEF11, and CRP. Each is linked with NT5DC4 in more than 1 cancer types. Because this analysis shows association rather than direction, both NT5DC4-to-partner and partner-to-NT5DC4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR1L1 grouped by NT5DC4-low versus NT5DC4-high in LUNG_SCLC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NT5DC4→partner) and Y-score (partner→NT5DC4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	OR1L1 →	+0.045	+5.029	<.001	.006	3	1
LUNG_SCLC	PRAMEF11 →	+0.026	+5.029	<.001	.006	3	1
LARGE_INTESTINE	CRP →	+0.072	+4.415	<.001	.007	3	1
BREAST	KRTAP10-1 →	+0.019	+5.169	<.001	.005	3	1
BREAST	OOSP4B →	+0.040	+5.781	<.001	.001	3	1
LUNG_NSCLC_LUAD	ZNF735 →	+0.026	+4.947	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 6 associations by consensus.

OR1L1 by NT5DC4 expression — LUNG_SCLC

Explore this box plot interactively →