NT5DC3

Across TCGA patient cohorts, NT5DC3 mutation is significantly associated with the RNA expression of many other genes, with 3,405 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NT5DC3-associated genes across cancer lineages are RNA5SP422, RNA5SP411, and KIF23. Each is linked with NT5DC3 in more than 2 cancer types. Because this analysis shows association rather than direction, both NT5DC3-to-partner and partner-to-NT5DC3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP422 grouped by NT5DC3-low versus NT5DC3-high in LUSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NT5DC3→partner) and Y-score (partner→NT5DC3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUSC	RNA5SP422 →	+0.423	+4.733	.003	.004	3	3
LUSC	RNA5SP411 →	+0.564	+4.733	<.001	.004	3	3
UCEC	KIF23 →	+0.563	+3.480	.003	.002	3	3
UCEC	SNRPD1 →	+0.467	+2.212	<.001	<.001	3	3
CESC	OR51A8P →	+0.090	+5.539	.009	.004	3	2
KIRC	PGAM1P13 →	+0.058	+5.509	<.001	.004	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,405 associations by consensus.

RNA5SP422 by NT5DC3 expression — LUSC

Explore this box plot interactively →