NT5DC1

Across TCGA patient cohorts, NT5DC1 mutation is significantly associated with the RNA expression of many other genes, with 2,604 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NT5DC1-associated genes across cancer lineages are RNA5SP519, RNA5SP417, and IGLCOR22-2. Each is linked with NT5DC1 in more than 1 cancer types. Because this analysis shows association rather than direction, both NT5DC1-to-partner and partner-to-NT5DC1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP519 grouped by NT5DC1-low versus NT5DC1-high in LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NT5DC1→partner) and Y-score (partner→NT5DC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	RNA5SP519 →	+0.533	+5.712	<.001	.003	3	2
UCEC	RNA5SP417 →	+0.346	+2.181	.002	.001	3	2
LIHC	IGLCOR22-2 →	+0.161	+5.355	<.001	.005	3	1
LIHC	RNA5SP342 →	+0.726	+5.186	<.001	.007	3	1
LIHC	RNU6-158P →	+0.433	+5.108	<.001	.008	3	1
LIHC	LINC02366 →	+0.091	+6.008	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,604 associations by consensus.

RNA5SP519 by NT5DC1 expression — LUAD

Explore this box plot interactively →