NT5C3B

Across TCGA patient cohorts, NT5C3B mutation is significantly associated with the RNA expression of many other genes, with 531 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NT5C3B-associated genes across cancer lineages are RNU5E-9P, RN7SL654P, and RN7SL837P. Each is linked with NT5C3B in more than 1 cancer types. Because this analysis shows association rather than direction, both NT5C3B-to-partner and partner-to-NT5C3B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU5E-9P grouped by NT5C3B-low versus NT5C3B-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NT5C3B→partner) and Y-score (partner→NT5C3B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNU5E-9P →	+0.272	+4.148	<.001	.006	3	2
UCEC	RN7SL654P →	+0.146	+3.109	<.001	.007	3	2
SKCM	RN7SL837P →	+0.136	+5.993	<.001	.001	3	2
COAD	TRAJ46 →	+1.273	+4.516	<.001	.009	3	2
COAD	RN7SL98P →	+0.322	+4.693	<.001	.007	3	2
BRCA	PLCE1P1 →	+0.239	+7.731	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 531 associations by consensus.

RNU5E-9P by NT5C3B expression — UCEC

Explore this box plot interactively →