NT5C2

Across TCGA cell cohorts, NT5C2 mutation is significantly associated with the RNA expression of many other genes, with 352 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible NT5C2-associated genes across cancer lineages are AVP, CDH20, and STXBP3. Each is linked with NT5C2 in more than 1 cancer types. Because this analysis shows association rather than direction, both NT5C2-to-partner and partner-to-NT5C2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, AVP grouped by NT5C2-low versus NT5C2-high in BLOOD_Lymphoma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NT5C2→partner) and Y-score (partner→NT5C2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	AVP →	+0.031	+5.209	<.001	.005	3	1
LARGE_INTESTINE	CDH20 →	+0.081	+3.444	.002	<.001	3	1
LARGE_INTESTINE	STXBP3 →	+0.553	+3.212	<.001	.006	3	1
LARGE_INTESTINE	RCN2 →	+0.674	+3.212	<.001	.006	3	1
LARGE_INTESTINE	CCNI →	+0.569	+3.299	.005	.004	3	1
LARGE_INTESTINE	ALDH6A1 →	+1.014	+3.212	.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 352 associations by consensus.

AVP by NT5C2 expression — BLOOD_Lymphoma

Explore this box plot interactively →