NT5C1B

mutation — cross-omics
Cross-omicsMUTATION → PROTEIN-RPPAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, NT5C1B mutation is significantly associated with the total protein of many other genes, with 33 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NT5C1B-associated genes across cancer lineages are Src, BRCA2, and 14-3-3_beta. Each is linked with NT5C1B in more than 1 cancer types. Because this analysis shows association rather than direction, both NT5C1B-to-partner and partner-to-NT5C1B results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NT5C1B→partner) and Y-score (partner→NT5C1B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
SKCMSrc →-0.268-2.070<.001.00132
SKCMBRCA2 →-0.128-2.299.048.03032
UCEC14-3-3_beta →-0.107-1.973.001.00832
UCECeIF4E →+0.147+1.222.031.03532
UCECMEK1 →+0.331+2.584.005.00132
UCECp21 →+0.127+1.222.041.03532
Each partner links to its Q-omics profile. Showing the 6 strongest of 33 associations by consensus.

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