NSUN7

Across TCGA patient cohorts, NSUN7 mutation is significantly associated with the RNA expression of many other genes, with 1,753 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NSUN7-associated genes across cancer lineages are PGAP2, SIGLEC27P, and NFIA-AS2. Each is linked with NSUN7 in more than 2 cancer types. Because this analysis shows association rather than direction, both NSUN7-to-partner and partner-to-NSUN7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PGAP2 grouped by NSUN7-low versus NSUN7-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NSUN7→partner) and Y-score (partner→NSUN7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	PGAP2 →	+0.422	+2.600	<.001	<.001	3	3
COAD	SIGLEC27P →	+0.075	+4.807	<.001	.004	3	2
SKCM	NFIA-AS2 →	-0.718	-2.656	.003	<.001	3	2
SKCM	MEF2C-AS2 →	+0.090	+1.736	.002	.004	3	2
CESC	NBPF5P →	+0.068	+4.384	<.001	.008	3	2
BLCA	RN7SL219P →	+0.268	+3.080	.005	.004	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,753 associations by consensus.

PGAP2 by NSUN7 expression — UCEC

Explore this box plot interactively →