NSUN7

Across TCGA cell cohorts, NSUN7 mutation is significantly associated with the RNA expression of many other genes, with 6 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible NSUN7-associated genes across cancer lineages are AVPR1B, IL31, and MDFIC2. Each is linked with NSUN7 in more than 1 cancer types. Because this analysis shows association rather than direction, both NSUN7-to-partner and partner-to-NSUN7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, AVPR1B grouped by NSUN7-low versus NSUN7-high in SKIN.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NSUN7→partner) and Y-score (partner→NSUN7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	AVPR1B →	+0.013	+5.415	<.001	.004	3	1
SKIN	IL31 →	+0.021	+4.977	<.001	.007	3	1
SKIN	MDFIC2 →	+0.155	+4.977	<.001	.007	3	1
LARGE_INTESTINE	GFRA4 →	+0.017	+3.345	.003	.007	3	1
LARGE_INTESTINE	OR10H5 →	+0.018	+3.347	<.001	.005	3	1
LARGE_INTESTINE	RTL3 →	+0.019	+3.347	.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 6 associations by consensus.

AVPR1B by NSUN7 expression — SKIN

Explore this box plot interactively →