NSUN6

Across TCGA patient cohorts, NSUN6 mutation is significantly associated with the RNA expression of many other genes, with 3,489 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NSUN6-associated genes across cancer lineages are RPL23AP84, GCNAP1, and MRPS15P1. Each is linked with NSUN6 in more than 2 cancer types. Because this analysis shows association rather than direction, both NSUN6-to-partner and partner-to-NSUN6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RPL23AP84 grouped by NSUN6-low versus NSUN6-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NSUN6→partner) and Y-score (partner→NSUN6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	RPL23AP84 →	+0.083	+3.923	<.001	.003	3	3
BLCA	GCNAP1 →	+0.247	+2.937	.002	.003	3	2
BLCA	MRPS15P1 →	+0.066	+2.975	<.001	.003	3	2
BLCA	C7orf77 →	+0.423	+4.768	<.001	<.001	3	2
READ	LINC00399 →	+0.487	+5.039	<.001	.008	3	2
READ	ANKRD26P2 →	+0.062	+5.421	.001	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,489 associations by consensus.

RPL23AP84 by NSUN6 expression — SKCM

Explore this box plot interactively →