NSUN6

Across TCGA cell cohorts, NSUN6 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,196 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible NSUN6-associated GO terms across cancer lineages are tRNA methylation, Positive regulation of cilium assembly, and mRNA 3'-end processing. Each is linked with NSUN6 in more than 13 cancer types. Because this analysis shows association rather than direction, both NSUN6-to-partner and partner-to-NSUN6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, tRNA methylation grouped by NSUN6-low versus NSUN6-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NSUN6→partner) and Y-score (partner→NSUN6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	tRNA methylation →	+0.069	+0.862	<.001	<.001	3	14
BONE	Positive regulation of cilium assembly →	+0.075	+0.709	.005	.001	3	12
OVARY	mRNA 3'-end processing →	+0.096	+0.971	<.001	<.001	2	12
SOFT_TISSUE	Subtelomeric heterochromatin formation →	+0.103	+0.607	<.001	<.001	3	11
BONE	Defense response to bacterium →	-0.110	-0.758	.005	.001	2	12
BONE	RNA surveillance →	+0.097	+0.794	<.001	.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,196 associations by consensus.

tRNA methylation by NSUN6 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →