NSRP1

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, NSRP1 mutation is significantly associated with the RNA expression of many other genes, with 1,208 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NSRP1-associated genes across cancer lineages are RNU5E-9P, RN7SL392P, and RNU1-17P. Each is linked with NSRP1 in more than 2 cancer types. Because this analysis shows association rather than direction, both NSRP1-to-partner and partner-to-NSRP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU5E-9P grouped by NSRP1-low versus NSRP1-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NSRP1→partner) and Y-score (partner→NSRP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
COADRNU5E-9P →+0.219+4.824<.001.00233
SKCMRN7SL392P →+0.076+4.147<.001.00833
UCECRNU1-17P →+0.190+2.350<.001.00232
UCECRNU1-57P →+0.143+3.662<.001.00132
COADRNU5D-1 →+0.919+4.278.008<.00132
COADTRAJ12 →+1.159+3.403<.001.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 1,208 associations by consensus.

RNU5E-9P by NSRP1 expression — COAD

Box plot of RNU5E-9P in NSRP1-low vs NSRP1-high samples in COAD.

Explore this box plot interactively →

Exploration