NSRP1

Across TCGA cell cohorts, NSRP1 mutation is significantly associated with the RNA expression of many other genes, with 34 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible NSRP1-associated genes across cancer lineages are SH3GL2, OCIAD1, and PPP2R5D. Each is linked with NSRP1 in more than 1 cancer types. Because this analysis shows association rather than direction, both NSRP1-to-partner and partner-to-NSRP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SH3GL2 grouped by NSRP1-low versus NSRP1-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NSRP1→partner) and Y-score (partner→NSRP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	SH3GL2 →	+1.855	+3.474	<.001	.003	3	1
LARGE_INTESTINE	OCIAD1 →	+0.560	+3.125	<.001	.008	3	1
LARGE_INTESTINE	PPP2R5D →	+0.791	+3.064	<.001	.009	3	1
LARGE_INTESTINE	SCGB2A1 →	+0.539	+3.392	<.001	.006	3	1
LARGE_INTESTINE	CPO →	+0.118	+3.514	<.001	.007	3	1
LARGE_INTESTINE	HIPK4 →	+0.102	+3.302	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 34 associations by consensus.

SH3GL2 by NSRP1 expression — LARGE_INTESTINE

Explore this box plot interactively →