NSMF

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, NSMF protein abundance is significantly associated with the RNA expression of many other genes, with 2,424 significant associations in total. GBM shows the largest number of these associations.

The most reproducible NSMF-associated genes across cancer lineages are LGALS1, SOX10, and KDELR3. Each is linked with NSMF in more than 1 cancer types. Because this analysis shows association rather than direction, both NSMF-to-partner and partner-to-NSMF results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, NSMF versus LGALS1 in GBM, with a Pearson correlation of -0.39.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NSMF→partner) and Y-score (partner→NSMF) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
GBMLGALS1 →-0.934-0.462<.001.00131
GBMSOX10 →+1.877+0.393<.001<.00131
GBMKDELR3 →-0.513-0.398<.001.00131
GBMC22orf31 →+0.297+0.358.004<.00131
GBMLMF2 →-0.302-0.309.001.00131
GBMRASL10A →+1.219+0.567<.001<.00131
Each partner links to its Q-omics profile. Showing the 6 strongest of 2,424 associations by consensus.

NSMF vs LGALS1 — GBM

Per-sample scatter of NSMF vs LGALS1 in GBM (Pearson r = -0.39).

Explore this scatter interactively →

Exploration