NSMCE4A

Across TCGA cell cohorts, NSMCE4A RNA expression is significantly associated with the go_rna of many other GO terms, with 4,903 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible NSMCE4A-associated GO terms across cancer lineages are DNA-templated DNA replication maintenance of fidelity, Mitochondrial DNA replication, and Recombinational repair. Each is linked with NSMCE4A in more than 15 cancer types. Because this analysis shows association rather than direction, both NSMCE4A-to-partner and partner-to-NSMCE4A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DNA-templated DNA replication maintenance of fidelity grouped by NSMCE4A-low versus NSMCE4A-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NSMCE4A→partner) and Y-score (partner→NSMCE4A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	DNA-templated DNA replication maintenance of fidelity →	+0.125	+0.760	.006	.003	3	16
BONE	Mitochondrial DNA replication →	+0.132	+0.698	<.001	<.001	3	16
SOFT_TISSUE	Recombinational repair →	+0.072	+0.717	.001	.003	3	16
BLOOD_Lymphoma	DNA replication →	+0.096	+0.811	<.001	<.001	3	15
BONE	Double-strand break repair →	+0.089	+0.711	.005	.004	3	15
SOFT_TISSUE	DNA recombination →	+0.066	+0.680	.002	.007	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,903 associations by consensus.

DNA-templated DNA replication maintenance of fidelity by NSMCE4A expression — BONE

Explore this box plot interactively →