NSMCE1-DT

Across TCGA pan-cancer cohorts, NSMCE1-DT RNA differs between tumor and matched normal tissue in 11 of 18 cancer types tested, making tumor–normal expression one of NSMCE1-DT’s most consistent transcriptional readouts.

The strongest signal is observed in colon adenocarcinoma (COAD), where NSMCE1-DT RNA is more highly expressed in tumor relative to normal tissue. In most cancer types NSMCE1-DT is over-expressed in tumor, although a few such as KICH and THCA show the opposite, repressed pattern.

COAD, LIHC, and CHOL are the cancer types where NSMCE1-DT tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in NSMCE1-DT RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
COAD	All	All	+0.172	<.001	9	view →
LIHC	Male	All	+0.164	<.001	7	view →
CHOL	All	II,III,IV	+0.730	.006	4	view →
KICH	All	All	−0.292	<.001	4	view →
KIRP	All	II,III,IV	+0.233	.010	4	view →
THCA	All	All	−0.142	.012	3	view →
LUSC	Male	III,IV	−0.274	.004	2	view →
STAD	All	All	+0.142	.028	2	view →
PRAD	All	All	+0.141	.018	2	view →
HNSC	All	All	+0.045	.028	2	view →
READ	All	All	+0.201	.029	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 11 strongest of 11 lineages.

NSMCE1-DT–COAD

Open the COAD breakdown →