NSFL1C

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, NSFL1C RNA expression is significantly associated with the go_rna of many other GO terms, with 3,349 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible NSFL1C-associated GO terms across cancer lineages are Regulation of protein localization to endoplasmic reticulum, Positive regulation of protein localization to endoplasmic reticulum, and Regulation by virus of viral protein levels in host cell. Each is linked with NSFL1C in more than 15 cancer types. Because this analysis shows association rather than direction, both NSFL1C-to-partner and partner-to-NSFL1C results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of protein localization to endoplasmic reticulum grouped by NSFL1C-low versus NSFL1C-high in KIDNEY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NSFL1C→partner) and Y-score (partner→NSFL1C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
KIDNEYRegulation of protein localization to endoplasmic reticulum →+0.121+0.929<.001.003316
KIDNEYPositive regulation of protein localization to endoplasmic reticulum →+0.124+0.929<.001.003315
CNSRegulation by virus of viral protein levels in host cell →+0.148+0.844<.001<.001312
BREASTEndosomal transport →+0.045+0.865.003.001312
LUNG_NSCLC_LUSCProtein depolymerization →+0.102+0.759.001.001213
SOFT_TISSUEProtein-containing complex disassembly →+0.072+0.986<.001.004212
Each partner links to its Q-omics profile. Showing the 6 strongest of 3,349 associations by consensus.

Regulation of protein localization to endoplasmic reticulum by NSFL1C expression — KIDNEY

Box plot of Regulation of protein localization to endoplasmic reticulum in NSFL1C-low vs NSFL1C-high samples in KIDNEY.

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Exploration