NRXN3

Across TCGA patient cohorts, NRXN3 RNA expression is significantly associated with the protein abundance of many other proteins, with 15,645 significant associations in total. GBM shows the largest number of these associations.

The most reproducible NRXN3-associated proteins across cancer lineages are SORBS2, NRBF2, and PSMB10_S230. Each is linked with NRXN3 in more than 4 cancer types. Because this analysis shows association rather than direction, both NRXN3-to-partner and partner-to-NRXN3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, NRXN3 versus SORBS2 in COAD, with a Pearson correlation of 0.23.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (NRXN3→partner) and Y-score (partner→NRXN3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	SORBS2 →	+0.502	+0.507	<.001	.005	3	5
CCRCC	NRBF2 →	-0.411	-0.638	<.001	.001	3	5
LUAD	PSMB10_S230 →	-0.822	-0.770	<.001	.007	3	4
HNSC	UPP1 →	-1.156	-0.905	<.001	.001	3	4
LUAD	UTRN →	+0.271	+0.853	<.001	<.001	3	4
LSCC	ZNF326 →	+0.287	+0.512	<.001	.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,645 associations by consensus.

NRXN3 vs SORBS2 — COAD

Explore this scatter interactively →