NRSN2

Across TCGA patient cohorts, NRSN2 mutation is significantly associated with the RNA expression of many other genes, with 830 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NRSN2-associated genes across cancer lineages are IGHV1OR15-4, RNU6-907P, and COPS8P1. Each is linked with NRSN2 in more than 1 cancer types. Because this analysis shows association rather than direction, both NRSN2-to-partner and partner-to-NRSN2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, IGHV1OR15-4 grouped by NRSN2-low versus NRSN2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NRSN2→partner) and Y-score (partner→NRSN2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	IGHV1OR15-4 →	+0.088	+2.937	<.001	.009	3	2
UCEC	RNU6-907P →	+0.228	+2.622	.008	.007	3	2
LIHC	COPS8P1 →	+0.080	+5.355	<.001	.005	3	1
LIHC	DBF4P2 →	+0.024	+5.758	<.001	.003	3	1
COAD	RNU4-85P →	+0.368	+3.899	<.001	.003	3	1
COAD	GOLGA8O →	+0.065	+4.131	.003	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 830 associations by consensus.

IGHV1OR15-4 by NRSN2 expression — UCEC

Explore this box plot interactively →