Across TCGA patient cohorts, NRN1L RNA expression is significantly associated with the go_rna of many other GO terms, with 6,710 significant associations in total. STAD shows the largest number of these associations.

The most reproducible NRN1L-associated GO terms across cancer lineages are Positive regulation of DNA repair, Peptidyl-proline modification, and Negative regulation of mRNA processing. Each is linked with NRN1L in more than 16 cancer types. Because this analysis shows association rather than direction, both NRN1L-to-partner and partner-to-NRN1L results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NRN1L→partner) and Y-score (partner→NRN1L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Positive regulation of DNA repair →	+0.047	+0.070	<.001	<.001	3	17
ESCA	Peptidyl-proline modification →	+0.046	+0.108	.001	<.001	3	15
STAD	Negative regulation of mRNA processing →	+0.052	+0.075	<.001	<.001	3	15
STAD	High-density lipoprotein particle assembly →	+0.050	+0.070	<.001	<.001	3	15
STAD	mRNA 3'-splice site recognition →	+0.039	+0.065	<.001	<.001	3	15
STAD	Nucleolar large rRNA transcription by RNA polymerase I →	+0.047	+0.079	<.001	<.001	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,710 associations by consensus.

Exploration

NRN1L survival (RNA) · tumor vs normal (RNA) · all NRN1L data types