Across TCGA cell cohorts, NRN1L RNA expression is significantly associated with the go_rna of many other GO terms, with 1,767 significant associations in total. BONE shows the largest number of these associations.

The most reproducible NRN1L-associated GO terms across cancer lineages are Taurine biosynthetic process, Alkanesulfonate biosynthetic process, and Centromeric sister chromatid cohesion. Each is linked with NRN1L in more than 6 cancer types. Because this analysis shows association rather than direction, both NRN1L-to-partner and partner-to-NRN1L results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NRN1L→partner) and Y-score (partner→NRN1L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Taurine biosynthetic process →	+0.824	+0.343	.003	.005	3	7
BONE	Alkanesulfonate biosynthetic process →	+0.824	+0.343	.003	.005	3	7
STOMACH	Centromeric sister chromatid cohesion →	-0.141	-0.243	<.001	.004	3	7
PANCREAS	Actin-mediated cell contraction →	-0.086	-0.232	<.001	.002	3	7
UPPER_AERODIGESTIVE_TRACT	Positive regulation of calcium ion import across plasma membrane →	-0.151	-0.401	<.001	.004	3	6
BLOOD_Leukemia	Lactate metabolic process →	-0.054	-0.296	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,767 associations by consensus.

Exploration

NRN1L survival (RNA) · tumor vs normal (RNA) · all NRN1L data types