NRM

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, NRM RNA expression is significantly associated with the protein abundance of many other proteins, with 17,147 significant associations in total. GBM shows the largest number of these associations.

The most reproducible NRM-associated proteins across cancer lineages are TOP2A, NASP, and MCM2. Each is linked with NRM in more than 7 cancer types. Because this analysis shows association rather than direction, both NRM-to-partner and partner-to-NRM results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, NRM versus TOP2A in UCEC, with a Pearson correlation of 0.37.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (NRM→partner) and Y-score (partner→NRM) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECTOP2A →+0.827+0.672<.001<.00138
GBMNASP →+0.615+0.549<.001<.00138
OVMCM2 →+0.716+1.124<.001<.00138
OVMCM3 →+0.873+1.216<.001<.00138
OVMCM4 →+0.838+1.067<.001<.00138
OVMCM5 →+0.729+1.107<.001<.00138
Each partner links to its Q-omics profile. Showing the 6 strongest of 17,147 associations by consensus.

NRM vs TOP2A — UCEC

Per-sample scatter of NRM vs TOP2A in UCEC (Pearson r = 0.37).

Explore this scatter interactively →

Exploration