NRK

Across TCGA patient cohorts, NRK protein abundance is significantly associated with the RNA expression of many other genes, with 5,364 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible NRK-associated genes across cancer lineages are SULF1, KLHL5, and SCNN1A. Each is linked with NRK in more than 2 cancer types. Because this analysis shows association rather than direction, both NRK-to-partner and partner-to-NRK results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, NRK versus SULF1 in BRCA, with a Pearson correlation of 0.42.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NRK→partner) and Y-score (partner→NRK) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	SULF1 →	+1.520	+1.571	.001	<.001	3	3
LUAD	KLHL5 →	+0.719	+1.377	.002	.002	3	3
BRCA	SCNN1A →	+1.647	+1.174	.002	.002	3	2
LSCC	BAG2 →	+0.848	+1.173	.002	.009	3	2
LSCC	DBN1 →	+0.738	+0.899	<.001	<.001	3	2
BRCA	CNTN3 →	+1.250	+1.171	<.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,364 associations by consensus.

NRK vs SULF1 — BRCA

Explore this scatter interactively →