Across TCGA patient cohorts, NRIR RNA expression is significantly associated with the protein abundance of many other proteins, with 10,418 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible NRIR-associated proteins across cancer lineages are OAS2, CMPK2, and IFIT1. Each is linked with NRIR in more than 9 cancer types. Because this analysis shows association rather than direction, both NRIR-to-partner and partner-to-NRIR results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (NRIR→partner) and Y-score (partner→NRIR) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	OAS2 →	+0.977	+0.919	<.001	<.001	3	10
HNSC	CMPK2 →	+0.870	+1.180	<.001	<.001	3	10
GBM	IFIT1 →	+1.078	+1.280	<.001	<.001	3	10
HNSC	IFIT2 →	+1.212	+1.099	<.001	<.001	3	10
HNSC	IFIT3 →	+1.219	+1.144	<.001	<.001	3	10
LSCC	ISG15 →	+1.071	+0.816	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,418 associations by consensus.

Exploration

NRIR survival (RNA) · tumor vs normal (RNA) · all NRIR data types