NRIP2

Across TCGA cell cohorts, NRIP2 mutation is significantly associated with the RNA expression of many other genes, with 4 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible NRIP2-associated genes across cancer lineages are TRIML1, SPATA8, and OR2T4. Each is linked with NRIP2 in more than 1 cancer types. Because this analysis shows association rather than direction, both NRIP2-to-partner and partner-to-NRIP2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TRIML1 grouped by NRIP2-low versus NRIP2-high in LUNG_NSCLC_LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NRIP2→partner) and Y-score (partner→NRIP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	TRIML1 →	+0.125	+4.371	<.001	.005	3	1
BLOOD_Lymphoma	SPATA8 →	+0.217	+4.867	<.001	.009	3	1
BLOOD_Lymphoma	OR2T4 →	+0.022	+5.209	<.001	.005	3	1
BLOOD_Lymphoma	OR4A47 →	+0.022	+5.643	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

TRIML1 by NRIP2 expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →