NRIP2

Across TCGA cell cohorts, NRIP2 mutation is significantly associated with the mutation status of many other genes, with 1,517 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible NRIP2-associated genes across cancer lineages are HPS5, CCDC83, and RIN2. Each is linked with NRIP2 in more than 2 cancer types. Because this analysis shows association rather than direction, both NRIP2-to-partner and partner-to-NRIP2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, HPS5 grouped by NRIP2-low versus NRIP2-high in BLOOD_Lymphoma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NRIP2→partner) and Y-score (partner→NRIP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	HPS5 →	+4.429	+5.247	.005	.005	1	3
BLOOD_Leukemia	CCDC83 →	+4.736	+5.560	.003	.003	1	3
LARGE_INTESTINE	RIN2 →	+4.087	+5.044	.001	.001	1	3
LARGE_INTESTINE	BRSK2 →	+3.350	+4.584	.003	.003	1	3
LARGE_INTESTINE	DHX16 →	+4.672	+5.329	<.001	<.001	1	3
LUNG_NSCLC_LUAD	ZC3H14 →	+5.339	+4.772	.004	.004	1	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,517 associations by consensus.

HPS5 by NRIP2 expression — BLOOD_Lymphoma

Explore this box plot interactively →