NRIP1

Across TCGA pan-cancer cohorts, NRIP1 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated NRIP1 data layer compared with 22 for mass-spec protein and 5 for mutation status.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where higher NRIP1 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated NRIP1 expression acts as an unfavorable survival marker, although some lineages such as CCRCC show a favorable association.

CCRCC, HNSC, and LUAD are the cancer types where NRIP1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CCRCC	DFS	Quartile	All	0.929	0.537	.008	18	view →
HNSC	DFS	Median	IV	0.515	0.947	.008	12	view →
LUAD	DFS	Median	All	0.199	0.696	.001	12	view →
LSCC	OS	Median	All	0.772	0.971	.006	8	view →
PDAC	OS	Median	III,IV	0.282	0.827	.038	3	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

NRIP1–CCRCC (DFS)

Open the CCRCC breakdown →